Relationship between Biological Factors and Organic Solvent Level in Handicraft Workers in Chiangmai

Jiaranai Khantipongse, Anongsin Danphaiboon, Channarong Chaisuwan, Supakij Khacha-ananda, Jaras Singkaew, Somkiat Tuamsang


The aim of this study is to detect the organic solvent-level (Acetone, Isopropaanol,Toluene, Trichloroethylene and Hexane) in handicraft workers’ blood from Chiangmai province and to evaluate the relation between the workers’ health. The knowledge from this study will be useful for workers. There are 2 groups of the workers in this study, exposure (n = 150) and non-exposure group (n = 150). The worker group is always contact to organic solvent during working, while the non-exposure group is not exposed or contact to organic solvent. Blood samples were collected at the end of the week. Organic solvents (parent compound) were detected by using Headspace-Gas Chromatography with Flame ionization detector (HS-GC-FID). Hematology and chemistry were also examined for evaluation of workers’ health status. The result was shown the level of Trichloroethylene in exposure group is higher than non-exposure group at statistic significant at p ≤ 0.05 (Man Whitney’s U test). The statistic relationships were shown on trichloroethylene level among number of monocytes (r = 0.77, p = 0.004) and blood urea nitrogen (r = 0.67, p = 0.038). There is no statistic significant of the relationship between organic solvent levels and working hours. According to the result, could be concluded that increasing of monocytes and BUN might be toxicity effect of exposed to trichloroethylene.

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